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THE STORY BEHIND PDGF

  • Ainsley Wharton
  • Jul 23
  • 2 min read

Updated: Aug 7

At Contour Collection, we’re obsessed with treatments that don’t just make skin look better—they actually help it heal and rebuild. One of the most powerful tools in true regenerative aesthetics?



This little protein has a big story, and we think you’ll love the science behind it.


Ariessence Pure PDGF

A DISCOVERY THAT CHANGED MEDICINE

In the 1990s, Harvard double‑doctorate Dr. Lynch made a breakthrough that would reshape wound healing and regenerative treatments. By meticulously sorting through donor blood, he isolated a chain of amino acids—the foundation of PDGF—and removed the original mRNA/DNA to create something we could replicate in a lab.


He didn’t just discover it. He pioneered it. Dr. Lynch built an entire platform around PDGF, sold it to Johnson & Johnson, and then—because visionaries never stop—bought it back. Today, there are over 120 patents protecting his work.



WHY PDGF MATTERS IN AESTHETICS

There are five known types of PDGF, but PDGF‑BB is the true standout. It’s clinically proven to stimulate:

  • Collagen types I, III, and VI

  • Hyaluronic acid (HA)

  • Elastin


That means firmer structure, better hydration, and improved elasticity—the exact building blocks your skin needs to look healthy, lifted, and luminous.



PURE SCIENCE, NOT JUST PLATELETS

Unlike PRP or PRF, PDGF‑BB isn’t taken from your own blood—it’s carefully created in a lab for incredible consistency and potency


Only three labs in the U.S. manufacture PDGF at this level. The one we offer at Contour Collection is so pure it’s made of just three ingredients:

  1. A 59‑dimer polypeptide

  2. Water

  3. Sodium acetate



RESULTS YOU CAN SEE AND FEEL

Clinical data shows PDGF‑BB outperforms PRP and PRF, with:

  • 200–400% more collagen types I, III, and VI

  • Up to 800% more HA and elastin production


During lab testing, the difference is striking. And in real life, clients are reporting improvements in tone, texture, even stubborn pigmentation and melasma, and a glow that can last up to a year.



FDA-APPROVED INNOVATION

PDGF isn’t just a theory—it’s backed by decades of clinical use:

  • Regranex® (1997): healing diabetic ulcers

  • GEM 21S® (2005): oral maxillofacial regeneration

  • Augment® Bone Graft (2015): rebuilding bone

  • Augment® Injectable (2018): soft‑tissue applications


Search PDGF-BB on FDA.gov and you’ll find over 1,200 white papers. This is proven science—now used in aesthetic medicine to unlock your skin’s natural potential.



FINAL THOUGHTS

At Contour Collection, we’re dedicated to harnessing the most advanced science to help your skin heal, renew, and truly glow from within. PDGF is more than just a breakthrough—it’s a trusted ally in your journey to healthier, more radiant skin. Ready to experience the next level of regeneration? Let’s make it happen together.






If you have any questions about PDGF, we are here to help! You can reach us at (720) 629-8921, or you can book a New Client Consultation to learn more. We're happy to answer any questions you may have and guide you through the process.

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