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EVERYTHING YOU NEED TO KNOW ABOUT PDGF

  • Ainsley Wharton
  • May 10
  • 3 min read

Updated: May 12

In the ever-evolving world of aesthetics, innovation is key—and one breakthrough is quietly transforming how we approach skin repair and rejuvenation. Say hello to PDGF+, or Platelet-Derived Growth Factor Plus—a pharmaceutical-grade powerhouse originally designed for medical healing and now reimagined for advanced aesthetic treatments. Unlike traditional PRP (platelet-rich plasma), which depends on your body’s condition for effectiveness, PDGF+ delivers unmatched consistency, potency, and results—every single time. Backed by over 15 years of clinical use and four FDA-approved medical applications, this lab-engineered formula is not just a trend—it’s a game changer. Whether you’re struggling with under-eye concerns, skin laxity, or loss of radiance, PDGF+ may be the skin-regenerating solution you’ve been waiting for.


Topical PDGF application post microneedling


WHAT IS PDGF+?


PDGF stands for Platelet-Derived Growth Factor, a naturally occurring protein in our bodies that plays a critical role in tissue repair and regeneration. While PRP relies on your own blood to deliver growth factors, PDGF+ is a lab-engineered, pharmaceutical-grade version that offers unmatched consistency, potency, and results. 


It's the powerhouse behind four FDA-approved medical treatments used in dentistry, orthopedics, and wound care-now reimagined for aesthetics.



Box of PDGF


WHY CHOOSE PDGF+ OVER PRP?

  • Extreme Potency: PDGF+ is 1,000 to 300,000 times stronger than PRP.

  • No Human-Derived Components: Just four clean, essential ingredients-Water, Sodium Acetate, Hyaluronic Acid, and sh-Polypeptide-59 Dimer.

  • 100% Consistency: Unlike PRP, which depends on your hydration, stress, or nutrition levels,

  • PDGF+ delivers the same powerful concentration every time.

  • Proven Results: With over 5 million patients treated in the past 15 years, its safety and efficacy are well-established.



HOW DOES PDGF+ WORK?

PDGF+ activates fibroblasts, the collagen-producing cells in your skin. The results?


  • Stronger, thicker skin

  • Natural collagen and elastin production

  • Improved skin tone and texture

  • Increased hyaluronic acid (HA) for plump, dewy hydration

  • Enhanced tissue regeneration, especially in delicate areas like the under-eyes



WHY IT'S A GAME CHANGER FOR UNDER-EYE REJUVENATION?

Under-eye hollowness, dark circles, and thinning skin are notoriously difficult to treat. Fillers can help with volume-but they don't improve skin quality. Lasers can smooth texture-but they don't plump. PDGF+ is different because it addresses the root cause: tissue degradation. With PDGF+, you're not just filling or resurfacing-you're stimulating your own skin to rebuild from within.



HOW CAN PDGF+ BE USED?

PDGF+ is incredibly versatile. It works beautifully on its own or paired with other skin treatments to amplify results.


Most popular treatments:

  • Microneedling + PDGF

    • Tiny controlled micro-injuries from microneedling allow PDGF+ to penetrate deeper, supercharging its effects:

      • Increased collagen production

      • Improved tone and texture

      • Reduced appearance of fine lines and scars

  • Under-Eye Injections

    • Increased collagen production

    • Improved tone and texture

  • Hair Injections

    • Stimulate hair growth



HOW TO PREPARE FOR YOUR PDGF+ TREATMENT:

  • 2 weeks before: Schedule around big events. Avoid dental work or vaccines.

  • 2 days before: No alcohol or NSAIDs. Consider Arnica tablets.

  • Day of: Eat a snack beforehand. We'll prep your skin-come as you are.


Do NOT schedule if you:

  • Have a skin infection or open lesion

  • Are pregnant or breastfeeding

  • Have taken Accutane in the past 6 months

  • Recently had an autoimmune treatment (within 24 hours)

  • Have an underlying or chronic autoimmune condition or flare up



FAQ'S:

  • When will I see results?

    • Initial improvements may appear in a few weeks, with visible changes between 2-4 weeks. Results last 6-12 months or more.

  • Is PDGF+ safe?

    • Yes. Backed by over 15 years of clinical use, 4 FDA approvals, and 5 million successful treatments.

  • How is Ariessence Pure PDGF+ different?

    • Pharmaceutical-grade, free from human cells or blood, made using advanced recombinant technology-guaranteeing purity, consistency, and safety.



FINAL THOUGHTS

PDGF+ isn’t just another skincare buzzword—it’s a scientifically backed, results-driven innovation that goes beyond surface-level improvements. By activating your skin’s natural regenerative processes, PDGF+ helps rebuild and strengthen from within, offering visible, lasting results in even the most delicate areas like the under-eyes. With unmatched potency, consistency, and a proven safety record, it’s no surprise that PDGF+ is becoming a go-to for those who want more than just a glow—they want real transformation. Whether used alone or paired with treatments like microneedling, this advanced growth factor therapy is redefining what’s possible in modern aesthetics.






If you have any questions about PDGF, we are here to help! You can reach us at (720) 629-8921, or you can book a New Client Consultation to learn more. We're happy to answer any questions you may have and guide you through the process.

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