PDGF VS. EXOSOMES

In the world of regenerative aesthetics, innovation is moving fast—and your skin is benefitting. Two of the most advanced skin rejuvenation treatments available today are Platelet-Derived Growth Factor (PDGF) and our Exosome Complex. Both offer powerful benefits for skin repair, collagen production, and post-procedure recovery.

But while they’re often mentioned in the same conversation, PDGF and exosomes work differently—and can be used strategically for best results.

Let’s break down the key differences between these two game-changing treatments, and why a rotational approach may be the smartest strategy for long-term skin health and glow.

WHAT IS PDGF+?

Platelet-Derived Growth Factor (PDGF) is one of the most powerful and well-researched growth factors naturally found in the body, known for its essential role in skin repair, collagen remodeling, and cellular regeneration. PDGF+ delivers an impressive 100,000 to 300,000 times the growth factor concentration found in competitive products—meaning fewer applications, faster results, and more satisfied clients.

What truly sets PDGF+ apart is its pharmaceutical-grade consistency and reliability. Unlike platelet-based treatments that depend on drawing and processing a patient’s own blood, PDGF+ provides a standardized dose with every application. This eliminates variability for providers while ensuring a safe, natural, and effective solution for clients. The formula is also exceptionally clean, containing only four ingredients: water, sodium acetate, hyaluronic acid, and sh-polypeptide-59 dimer—making it as pure as it is potent.

PDGF isn’t just promising—it’s proven. It serves as the active ingredient in four FDA-approved medical treatments (GEM 21S®, Augment®, Augment® Injectable, and Regranex®) and has helped treat over five million patients in the past 15 years. Now, that same trusted science is available in PDGF+, offering medical-grade regeneration tailored to modern aesthetic care.

It’s also incredibly versatile: PDGF+ can be used topically or injected, depending on the treatment approach. When injected, it penetrates deep into the dermis for structural skin regeneration. When applied topically—especially after microneedling, when absorption is maximized—it delivers powerful rejuvenating benefits at the surface level. This dual functionality makes PDGF+ a breakthrough solution for comprehensive skin revitalization.

Why We Love It:

• 100,000–300,000x the growth factor concentration of PRP

• Stimulates collagen and elastin for firmer, smoother skin

• Improves texture, tone, and skin thickness

• Reduces acne scars, fine lines, and redness

• Speeds healing and minimizes downtime post-microneedling

• Platelet-derived for clinically proven regeneration

WHAT IS OUR EXOSOME COMPLEX?

Exosomes are tiny, nano-sized vesicles that play a critical role in cell-to-cell communication. Released by nearly all cells in the body, exosomes act as messengers—carrying growth factors, cytokines, and other regenerative signals that help repair tissue and revitalize skin. In recent years, their benefits in skincare have been increasingly validated: in 2018, exosomes were used to help alleviate atopic dermatitis, and by 2020, a growing body of studies had confirmed their remarkable potential for skin rejuvenation.

Our Regenerative Exosome Complex takes this breakthrough science even further. Each application delivers over 5 billion lyophilized exosomes, along with 14 powerful growth factors, 19 peptides, hyaluronic acid, vitamin C, biotin coenzymes, and essential minerals—working together to deeply nourish, repair, and restore the skin for a continuous, healthy glow.

Exosomes are used topically and work primarily at the surface and epidermal levels. They’re especially effective when applied immediately after procedures like microneedling, laser, or radiofrequency treatments—helping to calm inflammation, accelerate healing, and enhance visible results. Whether you’re focused on recovery or radiance, exosomes offer a potent, science-backed solution for next-level skin rejuvenation.

Why We Love It:

• Boosts collagen and elastin production for firmer, more resilient skin

• Deeply hydrates and enhances skin elasticity

• Improves overall tone, brightness, and texture

• Calms inflammation and accelerates recovery after treatments

• Visibly reduces redness, irritation, and sensitivity

• Promotes a radiant, 24/7 healthy glow

• Powered by stem cell–derived exosome technology

HOW TO USE BOTH PDGF & EXOSOMES:

For optimal results and to ensure you’re covering all your growth factor bases, we recommend alternating between our PDGF Infusion and Exosome Glow treatments to achieve the most balanced, comprehensive skin rejuvenation. This strategy combines the powerful regenerative effects of PDGF with the glowy, hydrating benefits of exosomes—delivering true inside-out radiance that lasts.

For pricing and package details, please reach out to our Contour Concierge—we’re happy to guide you through the best plan for your skin goals.

FINAL THOUGHTS ON PDGF VS. EXOSOMES

Both PDGF and our Exosome Complex are at the forefront of regenerative aesthetics—and together, they create a dynamic duo for skin that looks healthier, firmer, and more luminous over time.

Looking to elevate your skin routine with smart, science-driven solutions? Ask your provider about a customized treatment plan that includes rotating PDGF and exosome protocols—because real skin transformation isn’t about choosing one or the other. It’s about knowing when to use both.

GET CONTOURED

If you have any questions about PDGF vs Exosomes, we are here to help! You can reach us at (720) 629-8921, or you can book a New Client Consultation to learn more. We're happy to answer any questions you may have and guide you through the process.